| 764688 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
464 2SMALL (NCT04253145) phase I part: lurbinectidine (LUR) in combination with atezolizumab (ATZ) for second line extensive stage small cell lung cancer (ES-SCLC) patients (pts) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.464 |
Aix Santiago Ponce, Navarro Alejandro, Bernabe Reyes, Olmedo Maria Eugenia, Manuel Trigo Jose, Fraile Jon Zugazagoitia, Paz-Ares Luis |
| 764687 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
579 Exploiting tumor neoantigen-targeted immunotherapy in immunologically hot versus cold murine lung cancer models |
2021-11-01 |
10.1136/jitc-2021-sitc2021.579 |
Sun Changbo, Nagaoka Koji, Kobayashi Yukari, Nakajima Jun, Kakimi Kazuhiro |
| 764686 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
791 Multi-specific Guidance and Navigation Control (GNC) T cell engagers convert PDL1 adaptive resistance to drug sensitivity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.791 |
Khalili Jahan, Gilchrist Mark, Rickli Sarah, Toglia Daphne, Zhu Yi |
| 764685 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
602 AXL targeting with bemcentinb restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through innate immune cell mediated expansion of TCF1+ CD8 T cells |
2021-11-01 |
10.1136/jitc-2021-sitc2021.602 |
Li Huiyu, Liu Zhida, Liu Longchao, Zhang Hongyi, Han Chuanhui, Girard Luc, Park Hyunsil, Zhang Anli, Dong Chunbo, Ye Jianfeng, Rayford Austin, Peyton Michael, Li Xiaoguang, Avila Kim, Cao Xuezhi, Hu Shuiqing, Akbay Esra, Solis Luisa, Behrens Carmen, Hernandez-Ruiz Sharia, Wei Lu, Wistuba Ignacio, Heymach John, Chisamore Michael, Micklem David, Gabra Hani, Gausdal Gro, Lorens James, Li Bo, Fu Yang-Xin, Minna John, Brekken Rolf |
| 764684 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
511 Initial results of a phase 1 study of intratumoral ONCR-177, an oncolytic herpes-simplex virus-1 expressing five immunomodulatory transgenes, in subjects with advanced injectable tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.511 |
Park Jong Chul, Soliman Hatem, Falchook Gerald, Owonikoko Taofeek, Spreafico Anna, Massarelli Erminia, McKean Meredith, Chow Laura, Ott Patrick, Wesolowski Robert, Fountzilas Christos, Whalen Corey, Yanez Adrienne, Dupont Christopher, Auer Julia, Cheema Tooba, Goldberg John, Ashburn Ted, Puzanov Igor |
| 764683 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
170 Novel gene editing approach to enhance CD38-directed antitumor activity of primary human natural killer cells |
2021-11-01 |
10.1136/jitc-2021-sitc2021.170 |
Clara Joseph, Levy Emily, Reger Robert, Chakraborty Mala, Allan David, Childs Richard |
| 764682 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
488 Phase 1 trial of first-in-class anti-CD96 monoclonal antibody inhibitor, GSK6097608, monotherapy and combination with anti–PD-1 monoclonal antibody, dostarlimab, in advanced solid tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.488 |
Hamid Omid, Baxter Dawn, Easton Rachael, Siu Lilian |
| 764681 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
485 Long term results from a phase 1 trial of GEN-009, a personalized neoantigen vaccine, combined with PD-1 inhibition in advanced solid tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.485 |
Gillison Maura, Awad Mark, Twardowski Przemyslaw, Sukari Ammar, Johnson Melissa, Lackner Rudy, Stein Mark, DeCillis Arthur, Hernandez Richard, Price Jessica, Mancini Kevin, Shainheit Mara, Santone Gabriella, Shukor Syukri, Bicak Ece, Vemulapalli Vijetha, Tjon Emily, Flechtner Jessica, Davis Thomas, Cohen Roger |
| 764680 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
107 Armoring NKG2D CAR T cells with IL-18 improves in vivo anti-tumor activity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.107 |
Breman Eytan, Walravens Ann-Sophie, Gennart Isabelle, Velghe Amelie, Nguyen Thuy, Violle Benjamin, Huberty Fanny, Ramelot Nancy, Twyffels Laure, Gauthy Emilie, Iserentant Hannes, Gilham David |
| 764679 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
105 4–1BB and optimized CD28 co-stimulation enhances function of human mono- and bi-specific third-generation CAR T cells |
2021-11-01 |
10.1136/jitc-2021-sitc2021.105 |
Roselli Emiliano, Boucher Justin, Li Gongbo, Kotani Hiroshi, Spitler Kristen, Reid Kayla, Bulliard Yannick, Tu Nhan, Lee Sae Bom, Yu Bin, Locke Frederick, Davila Marco |
