Systems and methods are provided for estimating immune response effected by patient specific and plan specific radiation treatments (such as, e.g., SBRT). The systems and methods may take into account radiation impact on circulating immune blood cell types or sub-types, such as T lymphocytes, B lymphocytes, natural killer cells, erythrocytes, and/or neutrophils, and predict time dependent fractional blood count and cell kill following radiation therapy treatment. Additionally, the system, method, and computer readable medium provide parameters such as a dose dependent lymphocyte kill function and average net release rate of new lymphocytes into circulating blood (including promotion of cytotoxic T cells and suppression of lymphocytes in blood), which may be used for optimization of RT treatment plans.

• 출원번호 : 18935373
• 출원인 : Wijesooriya, Krishni
• 특허번호 :
• IPC : A61N-005/10(2006.01);G16H-010/60(2018.01);G16H-015/00(2018.01);G16H-020/40(2018.01);G16H-030/20(2018.01);G16H-050/50(2018.01);

PROBLEM TO BE SOLVED: To provide a nuclear fuel assembly.SOLUTION: A nuclear fuel assembly for nuclear reactor cores includes at least one fuel compact including a fuel compact coating tube defining an inner volume and a plurality of fuel pins each including a pin coating tube defining an inner volume and a fissile fuel arranged in the inner volume of the pin coating tube. The plurality of fuel pins are arranged in the inner volume of the fuel compact coating tube; and the sectional shape of the fuel compact is defined by the fuel compact coating tube.SELECTED DRAWING: Figure 1

• 출원번호 : 2024192839
• 출원인 : BWXT ADVANCED TECH LLC
• 특허번호 :
• IPC : G21C-003/324(2006.01)

PROBLEM TO BE SOLVED: To accurately predict a locomotorium disease in an estimation device, method, and program.SOLUTION: An estimation device includes at least one processor. The processor functions as a learned neural network for deriving an estimation result related to bone density of a bone part from a plain radiation image acquired by executing plain radiography of a subject including the bone part. The learned neural network is learned by using, as teacher data, (i) two radiation images acquired by imaging the subject including the bone part by radioactive rays with different energy distribution, (ii) the radiation image of the subject and a bone image showing the bone part of the subject, or (iii) the radiation image of the subject and a bone density image indicating the bone density of the bone part of the subject, and information related to the bone density of the bone part of the subject.SELECTED DRAWING: Figure 3

• 출원번호 : 2024192164
• 출원인 : FUJIFILM CORP
• 특허번호 :
• IPC : A61B-006/00(2024.01);A61B-006/50(2024.01);G06T-007/00(2017.01);

The invention relates to a radiometric level, density, mass flow and/or limit level measuring device, having a housing which accommodates a scintillator for generating radiation-induced light pulses, a photosensitive element for generating electrical signals based on the light pulses, and an evaluation unit for evaluating the electrical signals and for determining a measured value, wherein the scintillator is pressed within the housing against an abutment with a contact force (FP) by means of at least one return element, wherein the measuring device comprises a compensation device having a counterweight and a force transmission device, wherein by means of the force transmission device, the weight force (g2) of the counterweight can be transferred to the scintillator in such a way that said force acts on the scintillator against the weight force (g1) of the scintillator.

• 출원번호 : 18933408
• 출원인 : Körnle, Ralf
• 특허번호 :
• IPC : G01F-023/288(2006.01);G01T-001/20(2006.01);

본 발명에 따른 피시험 반도체 소자의 내방사선 평가 방법은, 피시험 반도체 소자를 중이온 장비에 제공하여 베이스 구간의 선형에너지전달(LET, linear energy transfer) 값에 따른 상기 피시험 반도체 소자의 단면적(cross section, σ) 값을 측정하는 단계, 상기 피시험 반도체 소자를 펄스 레이저 장비에 제공하고, 레이저 에너지 값에 따른 상기 피시험 반도체 소자의 단면적 값을 측정하는 단계, 및 상기 펄스 레이저 장비에 제공된 상기 레이저 에너지 값을 상기 선형에너지전달 값으로 변환시켜, 상기 베이스 구간을 제외한 나머지 구간의 선형에너지전달 값에 따른 상기 피시험 반도체 소자의 단면적 값을 유추하는 단계를 포함할 수 있다.

• 출원번호 : 10-2024-0151268
• 출원인 : 큐알티 주식회사
• 특허번호 : 10-2748332-0000
• IPC : G01R-031/311;G01R-031/00;H01S-003/00;

PROBLEM TO BE SOLVED: To provide high-throughput single-nucleus and single-cell libraries, and methods of production and use.SOLUTION: Provided herein are methods for preparing a sequencing library that includes nucleic acids from a plurality of single cells. In one embodiment, the method includes nuclear or cellular hashing which permits increased sample throughput and increased doublet detection at high collision rates. In one embodiment, the method includes normalization hashing, which aids in estimating and removing technical noise in cell-to-cell variation and increases sensitivity and specificity.SELECTED DRAWING: None

• 출원번호 : 2024190548
• 출원인 : ILLUMINA INC;UNIV OF WASHINGTON;
• 특허번호 :
• IPC : C40B-040/06(2006.01);C12N-005/10(2006.01);C12N-015/11(2006.01);C12Q-001/6869(2018.01);

The disclosure provides methods of promoting stem cell differentiation into mesoderm and endoderm cell lineages comprising, for example, contacting a stem cell with an agent that reduces or eliminates gene activity of one or more endogenous small nuclear ribonucleic acid (snoRNA) molecules, wherein the snoRNA molecules comprise SNORD97 and/or SNORD133. Also provided are isolated cardiomyocytes and compositions of the same, wherein the cardiomyocytes are produced using a method described herein.

• 출원번호 : 18932104
• 출원인 : LU, Zhipeng
• 특허번호 :
• IPC : C12N-005/077(2010.01);A61K-035/34(2015.01);C12N-009/22(2006.01);C12N-015/113(2010.01);

An apparatus for generating electricity via thermophotovoltaic (TPV) energy conversion is described. High efficiency is obtained by introducing a material into a combustion chamber that emits bright near-monochromatic visible light upon heating. This light is then directed to fall on an array of photovoltaic (PV) cells which convert the light to electricity. Heat and infrared radiation that is not absorbed by the PV cells is returned to the combustion chamber to further improve conversion efficiency.

• 출원번호 : 18932288
• 출원인 : FONG, Danielle A.
• 특허번호 :
• IPC : H02S-010/30(2006.01);F23K-005/00(2006.01);F23K-005/14(2006.01);

Particulate deposition rate on a photolithographic mask, particularly of tin (Sn) particles produced within an EUV light source, is reduced by producing turbulence within a radiation source chamber of the EUV light source. Turbulence can be produced by changing the temperature, pressure, and/or gas flow rate within the radiation source chamber. The turbulence reduces the number of particles exiting the EUV light source which could be deposited on the photomask.

• 출원번호 : 18931576
• 출원인 : Chen, Jui-Chieh
• 특허번호 :
• IPC : G03F-007/00(2006.01)

PROBLEM TO BE SOLVED: To stably exhibit properties such as conductivity and heat transfer, for example, as designed.SOLUTION: A spring member disposed between two bodies to be pressed facing each other in a first direction, comprises a first member, and a second member different from the first member, composed of a different material. The second member is curved or bent such that an intermediate portion in a second direction orthogonal to the first direction projects toward the other side of the first direction. The first member extends along the second member, and intersects the second member in the first direction. The first member is located in the intermediate portion in the second direction on the other side of the first direction from the second member, and also located in a portion other than the intermediate portion in the second direction on the one side in the first direction from the second member.SELECTED DRAWING: Figure 2

• 출원번호 : 2024191027
• 출원인 : NHK SPRING CO LTD
• 특허번호 :
• IPC : F16F-001/18(2006.01);H01L-023/36(2006.01);