The invention relates to a housing with a laser arrangement, having a lid, which comprises a portion transparent to laser radiation, and three substrates. Each substrate has at least one edge-emitting laser burr that is in the form of a resonator and has an output facet for the output of laser radiation at one wavelength, with the wavelengths of the laser burrs being different. At least one of the first, second and third substrates comprises at least one mirror element for deflecting, in the direction of the transparent portion, the laser radiation output by the corresponding edge-emitting laser burr. Moreover, each of the three substrates has a side face that is adjacent to the respective output facet or corresponds to the latter, and the side faces of two of the three substrates are at least partially adjacently opposite one another.

• 출원번호 : EP2024/079339
• 출원인 : AMS-OSRAM INTERNATIONAL GMBH
• 특허번호 :
• IPC : H01S-005/02255(2021.01);H01S-005/02208(2021.01);H01S-005/02257(2021.01);H01S-005/024(2006.01);H01S-005/026(2006.01);H01S-005/185(2021.01);H01S-005/40(2006.01);

Compositions, methods, kits, systems, and software are provided for detecting over-immunosuppression or under-immunosuppression in a renal transplant recipient undergoing treatment with immunosuppressive therapy. In particular, the methods utilize a urine-based metabolite signature that differentiates over-immunosuppressed or under-immunosuppressed renal transplant recipients from those with a stable graft with high accuracy. In some embodiments, nuclear magnetic resonance spectroscopy and/or liquid chromatography-mass spectrometry techniques are used to detect metabolite features that differentiate patients who are over-immunosuppressed or under-immunosuppressed from those with stable grafts. The subject methods can be used for monitoring a renal transplant recipient to avoid over-immunosuppression, which can lead to infections that cause graft dysfunction or lossor even death, as well as monitoring a renal transplant recipient to avoid under-immunosuppression, which can lead to graft dysfunction, subclinical graft rejection, or rejection.

• 출원번호 : US2024/051822
• 출원인 : OLARIS, INC.
• 특허번호 :
• IPC : G01N-024/08(2006.01);G01R-033/46(2006.01);G01N-033/50(2006.01);G01N-033/48(2006.01);G01R-033/465(2006.01);

Semiconductor devices with antennas and electromagnetic interference (EMI) shielding, and associated systems and methods, are described herein. In one embodiment, a semiconductor device includes a semiconductor die coupled to a package substrate. An antenna structure is disposed over and/or adjacent the semiconductor die. An electromagnetic interference (EMI) shield is disposed between the semiconductor die and the antenna structure to shield at least the semiconductor die from electromagnetic radiation generated by the antenna structure and/or to shield the antenna structure from interference generated by the semiconductor die. A first dielectric material and/or a thermal interface material can be positioned between the semiconductor die and the EMI shield, and a second dielectric material can be positioned between the EMI shield and the antenna structure. In some embodiments, the semiconductor device includes a package molding over at least a portion of the antenna, the EMI shield, and/or the second dielectric material.

• 출원번호 : 18918757
• 출원인 : Fay, Owen R.
• 특허번호 :
• IPC : H01L-023/552(2006.01);H01L-021/56(2006.01);H01L-023/31(2006.01);H01L-023/66(2006.01);H01Q-001/22(2006.01);

본 발명은 원자력발전소의 해체 시에 발생되는 액체 방사성폐기물의 통합 처리방법에 관한 것으로, 그 목적은 원자력발전소의 해체 시, 발생되는 다량의 액체방사성폐기물을 그 성상(性狀)에 따라 물 계통의 용액 상태인 저농도 액체 방사성폐기물, 물 계통의 현탁 및 슬러리 상태인 고농도 액체 방사성폐기물 및 유기용매 계통인 유기 액체 방사성폐기물로 구분하고, 구분된 각각의 저농도, 고농도 및 유기 액체 방사성폐기물을 각기 지정된 처리공정에 따라 안전하고 확실하게 처리될 수 있도록 하므로서 액체 방사성폐기물의 처리 결과물인 방사성폐기물 및 액체 방사성폐기물의 처리과정 중에 발생되는 2차 방사성폐기물의 발생량을 크게 저감시키는 동시에 액체 방사성폐기물의 처리에 대한 작업 생산성을 현저히 향상시키고, 처리비용도 크게 절감시킬 수 있도록 하는 것이며, 그 구성은 원자력발전소의 해체 시 발생되는 액체 방사성폐기물을 저농도 액체 방사성폐기물, 고농도 액체 방사성폐기물 및 유기 액체 방사성폐기물로 각각의 저장탱크에 구분하여 저장하는 액체 방사성폐기물 구분 저장단계와; 상기 액체 방사성폐기물 구분 저장단계에서, 각각의 저장탱크 내에 저장된 액체 방사성폐기물 내에 포함된 이물질, 오일, 불순물, 침전물 및 고체를 분리하여 수집하고, 유기물을 분해하는 전처리 단계와; 상기 전처리 단계를 통과한 액체 방사성폐기물 내에 함유된 방사성 오염물질을 제거하고, 방사성 오염물질이 제거된 응축액을 기액 분리하고, 배기체와 배출액을 생성하는 본처리 단계와; 상기 본처리 단계에서 기액 분리되어 배출되는 배기체와 배출액를 정화하고, 정화된 배기체 및 배출액을 건축물의 배기 및 배수계통으로 배출하는 후처리 단계로 구성되는 것을 특징으로 한다.

• 출원번호 : 10-2024-0140957
• 출원인 : 주식회사 엘씨젠
• 특허번호 : 10-2764066-0000
• IPC : G21F-009/20;B01D-046/56;B01D-005/00;C02F-001/08;C02F-001/40;C02F-001/44;C02F-001/46;C02F-001/52;G21F-009/02;G21F-009/10;G21F-009/12;

PROBLEM TO BE SOLVED: To provide axial and radial support for a welding portion on a core shroud.SOLUTION: A fixing device 30 is installable on an outer circumferential surface 32 of a reactor core shroud 12 and in contact with an inner circumferential surface of a pressure vessel. The fixing device includes a base 48 configured to contact the outer circumferential surface of the reactor core shroud. The fixing device also includes a radial expansion device 56 including an actuator 62, a stationary support portion 58 fixed to the base, and a movable contact portion 60. The radial expansion device is configured such that the movable contact portion can be moved along the stationary support portion by means of the actuator in order to radially push the movable contact portion into an inner circumferential surface of the pressure vessel.SELECTED DRAWING: Figure 3

• 출원번호 : 2024180768
• 출원인 : FRAMATOME INC
• 특허번호 :
• IPC : G21C-019/02(2006.01)

Described is a method and a unit (1) for inspecting a strip (N), which has a succession of work features (L) positioned along the direction of extension of the strip (N). The method comprises moving the strip (N) along a feed path passing through the inspection unit (1). In unit (1), the strip (N) is supported and guided by a supporting wall (2) which is configured to be transmissive to radiation in a predetermined wavelength interval. The strip (N) and the supporting wall (2) are radiated by means of an emitter (10) located in the inspection unit (1), with a radiation whose wavelength is within the predetermined wavelength interval. Subsequently, the residual radiation arriving from the other side of the strip (N) is received by a detector (20) and analysed by a processing unit to obtain at least one piece of information relating to a dimensional and/or quality parameter of the work features (L) present on the strip (N).

• 출원번호 : IB2024/060144
• 출원인 : G.D S.P.A.
• 특허번호 :
• IPC : G01N-021/89(2006.01);G01N-021/88(2006.01);

The present disclosure provides anti-ULBP2 antibodies or antigen binding fragments thereof, including bispecific. The antibodies are administered in combination with a chemotherapy agent, a radiation therapy, and/or an immune checkpoint inhibitor for treatment of basal squamous cancer. The present disclosure also relates to methods and kits for detecting a predisposition to, determining the risk of, and guiding therapy for ULBP2 related disorders.

• 출원번호 : US2024/051568
• 출원인 : EVOLVEIMMUNE THERAPEUTICS, INC.;MARTOMO, Stella, Aviaty;
• 특허번호 :
• IPC : C07K-016/28(2006.01);A61K-047/68(2017.01);

PROBLEM TO BE SOLVED: To provide an improved method, system, and apparatus for EMR-based (e.g., laser-based) tissue treatment.SOLUTION: A cooling element 150 includes a frame containing one or more data. The cooling element also includes a first window 112 including a first proximal surface and a first distal surface. The first window is sealed within the frame. The cooling element further includes a second window 118 sealed within the frame. The second window includes a second proximal surface and a second distal surface. The second window is configured to contact a target tissue or a tissue adjacent to the target tissue via the second distal surface. Additionally, the cooling element includes a cooling agent chamber arranged between the first distal surface of the first window and the second proximal surface of the second window and configured to accept a cooling agent 116. The first window, the second window, and the cooling agent chamber are configured to receive electromagnetic radiation (EMR) and transmit a part of the received EMR to the target tissue.SELECTED DRAWING: Figure 1

• 출원번호 : 2024180939
• 출원인 : AVAVA INC
• 특허번호 :
• IPC : A61B-018/20(2006.01)

An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

• 출원번호 : 18917231
• 출원인 : Dalvi, Cristiano
• 특허번호 :
• IPC : A61B-005/1455(2006.01);A61B-005/00(2006.01);

An apparatus and method produce, from a Gaussian laser pulse, a sequence of laser rings having a spatiotemporal configuration such that impingement of the laser rings on a surface of a nuclear material in a target assembly produces constructively interfering shock waves that converge on a focal region of the nuclear material, thereby producing sufficient pressures and temperatures to form tritium in the focal region. The temporal and/or spatial intervals between the concentric pulsed laser rings are adjusted to substantially match propagation times of impingement from one ring to the next in a shock propagation layer of the target assembly. A second laser or neutron tube may be used to create a cavitation bubble at the focus. In addition to the shock waves generated in the plane of the surface, through-plane shock waves can be generated to increase the overall shock pressure.

• 출원번호 : 18917271
• 출원인 : Massachusetts Institute of Technology
• 특허번호 :
• IPC : G21G-001/12(2006.01);G21B-001/03(2006.01);G21B-001/13(2006.01);G21B-001/19(2006.01);G21B-001/23(2006.01);G21G-001/00(2006.01);