A radiation detector includes a radiation-sensitive semiconductor substrate, a cathode electrode disposed over a first surface of the radiation-sensitive semiconductor material substrate, and at least one anode electrode disposed over a second surface of the radiation-sensitive semiconductor material substrate, where the at least one anode electrode includes a semiconductor material layer including cadmium sulfide located between a metallic material and the semiconductor material substrate. In one embodiment, the radiation-sensitive semiconductor substrate includes cadmium zinc telluride (CZT), and the semiconductor material layer includes Cd1-xZnxTeyS1-y, where 0≤x≤0.5 and 0≤y≤0.5. Further embodiments include methods of fabricating a radiation detector that include exposing a surface of a radiation-sensitive semiconductor material substrate to a gas containing hydrogen sulfide at an elevated temperature to form a sulfide-containing semiconductor material layer.

• 출원번호 : 18914522
• 출원인 : TIEDJE, Thomas
• 특허번호 :
• IPC : G01T-001/24(2006.01);H01L-027/146(2006.01);

본 발명은 일라이트를 포함하여 원적외선 방사 및 혈액 순환 기능이 개선된 남성용 라이너에 관한 것으로, 소변이 통과하도록 다수의 홀이 형성된 펄프 소재로 구성된 상면시트, 상기 상면시트의 하면에 위치하여 상기 다수의 홀을 통해 유입되는 소변이 흡수되도록 내부에 펄프 부직포를 포함하는 흡수층 및 상기 흡수층의 하면에 위치하여 상기 흡수층에 흡수된 소변이 누출되지 않도록 식물성 바이오매스 유래의 폴리우레탄 수지를 포함하는 생분해성 필름을 포함하는 방수층을 포함하며, 상기 흡수층은 흡수층 전체 100 중량부 대비 원적외선 방사제인 일라이트 5 내지 25 중량부, 흡수제 60 내지 80 중량부를 포함하며, 이들의 흡수층 전체 중량부의 합이 100을 넘지 않도록 구성된 것을 특징으로 하는 일라이트를 포함하여 원적외선 방사 및 혈액 순환 기능이 개선된 남성용 라이너를 제공하며,항균 효과를 통해 각종 염증 발생을 예방할 수 있으며, 고흡수성 수지(SAP) 대신 흡수제로 실리카겔, 규조토 분말 등을 포함해 환경 오염이나 인체 유해성에 대한 우려가 없으면서도 소변에 대한 흡수 성능이 우수할 수 있다.

• 출원번호 : 10-2024-0138347
• 출원인 : 주식회사 올담
• 특허번호 :
• IPC : A61F-013/471;A61F-013/15;A61F-013/511;A61F-013/53;A61F-013/84;

본 발명에 따른 방사선 측정 및 제염을 수행하는 로봇 장치는, 측정 대상물의 표면 중에서 방사선 측정의 대상이 되는 측정 대상 영역으로부터 방사선을 측정하는 방사선 측정 기능을 수행하여 방사선 세기값을 나타내는 방사능 세기 신호를 생성하는 센싱부; 상기 방사선 세기값 및 상기 방사선 세기값에 대응되는 방사선 측정 위치에 기초하여 상기 측정 대상물의 표면 중에서 제염의 대상이 되는 제염 대상 영역을 설정하는 프로세서; 및 상기 제염 대상 영역에 포함된 상기 측정 대상물의 표면을 연삭하여 상기 측정 대상물에 대해 제염을 하는 제염 기능을 수행하는 연삭부;를 포함할 수 있다.

• 출원번호 : 10-2024-0138567
• 출원인 : 주식회사 크라운 기술지주
• 특허번호 : 10-2788842-0000
• IPC : G01T-001/167;B25J-011/00;B25J-013/08;B25J-015/00;B25J-005/00;G01T-001/169;G01T-007/00;G21F-009/00;

We describe compositions of DNA donor molecules compatible with various gene insertion methods with major advantages for delivery, nuclear localization, and immune evasion. The modified DNA donor molecules are largely single stranded but contain short regions of double-strand DNA to reconstitute enzyme binding sites, and can be combined with other approaches to enhance donor recruitment into the nucleus.

• 출원번호 : US2024/051099
• 출원인 : THE GENERAL HOSPITAL CORPORATION
• 특허번호 :
• IPC : C12N-009/00(2006.01);C12N-015/90(2006.01);

The present invention relates to a beta-lactamase substrate compound for electrochemical detection of beta-lactamases, wherein the beta-lactamase substrate compound is according to formula (I), wherein β is hydrogen, C-C alkyl, C-C fluoroalkyl or is according to formula (II), wherein X is S or O, and Ris C-C alkyl, optionally comprising one or more carbonyl, hydroxyl, ether, ester or carboxyl functional groups; and R is selected from the group consisting of 4-cyanobenzyll, 4-nitrobenzyl, 4-sulfonebenzyl, 2,4-dicyanobenzyl, 2-nitro-4-cyanobenzyl, 3,4-dinitrobenzyl and 3,5-dinitrobenzyl, wherein the beta-lactamase substrate compound is hydrolysable by a beta-lactamase; and wherein the beta-lactamase substrate compound has a degradation at 4 °C equal to or lower than 50 % after 4 weeks and equal to or lower than 70 % after 18 weeks, and/or a degradation at 20 °C equal to or lower than 80 % after 4 weeks and equal to or lower than 85 % after 18 weeks, wherein the degradation is determined from the difference of the integration of nuclear magnetic resonance measurement signals of the beta-lactamase substrate compound and of dimethylformamide. The invention further relates to an electrochemical detection method for determination of the presence of bacteria producing beta-lactamases in a sample using the beta-lactamase substrate compound according to the invention.

• 출원번호 : EP2024/078641
• 출원인 : CORIS BIOCONCEPT
• 특허번호 :
• IPC : C07D-501/60(2006.01);C12Q-001/04(2006.01);G01N-027/48(2006.01);

The invention relates to a multilayer electrothermal structure and to a method for manufacturing the multilayer electrothermal structure. The structure includes a layer comprising graphene, wherein the layer is arranged as a thermoelectric element for emitting infrared radiation through a front face of the structure. The structure includes a reflective layer for redirecting infrared radiation from a rear face of the structure to the front face.

• 출원번호 : IB2024/059945
• 출원인 : GRAPHENATON TECHNOLOGIES SA
• 특허번호 :
• IPC : H05B-003/14(2006.01);H05B-003/34(2006.01);

A system for inactivating a pathogen in air, the system including a far-UV radiation source and an air filtration system. The far-UV radiation source and the air filtration system are operationally linked. The air filtration system can be configured for removing PM2.5 particles from air. The disclosure also provides a far-UV apparatus and a method for inactivation of a pathogen in air.

• 출원번호 : US2024/051116
• 출원인 : THE OSLUV PROJECT
• 특허번호 :
• IPC : F24F-008/22(2021.01);A61L-002/10(2006.01);A61L-009/20(2006.01);A61L-002/26(2006.01);F24D-015/00(2022.01);

PROBLEM TO BE SOLVED: To provide modeling of TDP-43 proteinopathy.SOLUTION: Disclosed herein is the discovery that neither nuclear localization signal (NLS) nor prion-like domain (PLD) of TDP-43 is necessary for embryotic stem cell culture and differentiation into motor neurons in vitro. The capability of ES cells to express TDP-43 variants and differentiate into neurons exhibiting an ALS-like phenotype (the TDP-43 variants redistribute to and aggregate in the cytoplasm, and fail to regulate cryptic exon splicing) allows these cells to act as a model of TDP-43 proteinopathy for the testing of candidate therapeutic agents that may resolve such proteinopathy. Further, these ES cells may be used for successfully generating a non-human animal such as a mouse exhibiting characteristic symptoms of ALS, for use in the search of candidate agents useful for the treatment of TDP-43 proteinopathy.SELECTED DRAWING: None

• 출원번호 : 2024179276
• 출원인 : REGENERON PHARMACEUTICALS INC
• 특허번호 :
• IPC : C12N-005/10(2006.01);C12N-015/12(2006.01);C12N-015/113(2010.01);C12N-005/0735(2010.01);C12Q-001/02(2006.01);C12N-005/0793(2010.01);C12N-015/09(2006.01);A01K-067/027(2024.01);C07K-014/46(2006.01);G01N-033/15(2006.01);G01N-033/50(2006.01);

A method for removing a layer of material (3) from a substrate (4), the method comprising irradiating the layer (3) and the substrate (4) with a pulse of laser radiation (1, 18, 19), wherein the pulse of laser radiation (1, 18, 19) comprises photons with an energy between 0.54 and 0.9 eV, and wherein the layer (3) comprises material that has an electronic energy bandgap larger than 1.0 eV.

• 출원번호 : GB2024/052625
• 출원인 : PULSE INVESTMENTS UK LIMITED
• 특허번호 :
• IPC : B08B-007/00(2006.01);B23K-026/40(2014.01);

An energy storage system converts variable renewable electricity (VRE) to continuous heat. Intermittent electrical energy heats a solid medium. Heat from the solid medium is delivered continuously on demand. An array of bricks incorporating internal radiation cavities is directly heated by thermal radiation. The cavities facilitate rapid, uniform heating via reradiation. Heat delivery via flowing gas establishes a thermocline which maintains high outlet temperature throughout discharge. Gas flows through structured pathways within the array, delivering heat which may be used for processes including calcination, hydrogen electrolysis, steam generation, and thermal power generation and cogeneration. Low temperature waste heat from energy production can be recovered and used to improve overall system efficiency.

• 출원번호 : US2024/051145
• 출원인 : RONDO ENERGY, INC.
• 특허번호 :
• IPC : F01K-003/18(2006.01);F01K-013/00(2006.01);F01K-017/02(2006.01);