PROBLEM TO BE SOLVED: To provide a method for imaging HDAC enzyme by using a compound useful for inhibiting a histone deacetylase (HDAC) enzyme, a compound useful for treating diseases related to irregular development level and/or activity of the HDAC enzyme (a marking compound or non-marking compound), as well as radiation marking compounds.SOLUTION: A compound shown in a formula below is used. (wherein, X1 is -N (RN)- or -CH (RC)-; X2 is CR2 or N; X3 is CR3 or N; RN is H, C1-6 alkyl, or C1-6 haloalkyl; RC is H, C1-6 alkyl, or C1-6 haloalkyl; L1 is bonded or C1-6 alkylene group; L2 is bonded or C1-6 alkylene group; R1 is C1-6 alkyl, C1-6 alkoxy, C3-10 cycloalkyl, or C6-10 aryl; R2,R3,R4 and R5 are H, C1-6 alkyl, halo, or C1-6 haloalkyl.)SELECTED DRAWING: None
- 출원번호 : 2024172020
- 출원인 : GENERAL HOSPITAL CORP
- 특허번호 :
- IPC : C07C-251/38(2006.01);A61P-043/00(2006.01);A61K-049/10(2006.01);A61P-035/00(2006.01);A61P-035/02(2006.01);A61P-029/00(2006.01);A61P-025/00(2006.01);A61P-025/28(2006.01);A61P-025/24(2006.01);A61P-025/18(2006.01);A61P-025/14(2006.01);A61K-031/16(2006.01);A61K-031/44(2006.01);C07D-213/82(2006.01);